Denisse Moralli was born and raised in the suburbs of Buenos Aires and spent her childhood helping her grandmother tailor clothes. As a child, she used to cycle around the town and imagine the interior of the buildings in the surrounding areas. During her school time, drawing and fine arts were her favorite subjects, which encouraged Denisse to start studying at The University of Buenos Aires (UBA) at the Faculty of Architecture and Urbanism (FADU) in 2004.
During her years there she was awarded several prizes for architectural design and was invited to join the faculty team.